The factors For selecting Medication For the Patient

SINCE The second world war, medical science has progressed into a stage where competitive medications are around to treat the identical ailment in different people. This is not nearly brands (that is a trade issue) but generic drugs (that is a scientific issue). On this report, we shall go through the various factors that decide selecting a selected drug.

Safety: The subsequent sub-criteria have to be considered beneath the criterion of safety:

* Acute therapeutic index: If your patient’s condition is acute, how effective is really a particular drug even though they have certain side-effects provided that the acuteness in the condition is lowered? Example: narcotic pain-killers work well in healing pain but come with the potential side-effect of addiction.

* Long-term safety: medication directory could be safe in short-term treatment, so how safe it is in long-term treatment? Example: antibiotics are acceptable in short-term treatment, but could have undesirable effects in the event of prolonged use.

* Drug-drug interaction risk: Medicine is chemicals, and several chemicals answer make a different chemical, that have an effect which could harm the patient or aggravate his/her condition. Example: A tricyclic anti-depressant and alcohol interact to produce a new condition that warrants separate treatment.

Drug-drug interaction risk is of 2 types:

· Pharmacokinetic: In this kind of drug-drug interaction, two drugs, separate from the other person, have certain effects using one or higher body processes (e.g., metabolism) that affects the performance in the other. Example: Darvocet-N (propoxyphene and acetaminophen) inhibits the act of a liver enzyme that Lexapro (escitalopram) is determined by for the metabolism. This will cause a boost in the side-effects of Lexapro.

· Pharmacodynamic: Here, two or more drugs actually generate the same impact on the identical organ, thus improving the total, added effect. Example: Lexapro has certain side-effects for example drowsiness and fatigue. Darvocet-N also acts similarly around the brain. Thus, the side-effects of the two medicine is more intense.

Tolerability: A medicine could be effective however, not tolerable by all patients. Example: Allergies to a particular drugs in a few people. Short-term and long-term tolerability need to be taken into consideration. Efficacy: A medicine isn’t equally efficient at all patients. For example, some patients with depression or panic disorders experience relief from escitalopram, but there are many who don’t, who therefore need to be prescribed an alternative anti-depressant. The rate of beginning of therapeutic action is a vital key to be looked at too.

Cost: Cost does not necessarily mean the price of acquisition of some medicine alone. It ought to also cover the price of management of a complication which could arise from using an alternative drug. Example: Within a person who insists on taking alcohol yet must be treated for depression is usually administered an SSRI drug because they drugs don’t potentiate the effects of alcohol, whereas another gang of anti-depressants (for example tricyclics) can cause a whole new overuse injury in such patients, which could need a different and expensive treatment. Therefore, it’s easier to prescribe the more costly escitalopram rather than cheaper tricyclic such patients.

Simplicity of treatment: The best mode of administration is preferred. If you find an alternative between an injection and oral administration, aforementioned is preferred if the efficacy of the two modes is the identical. Or, local application is preferred to the oral route where possible; e.g., antibiotic management of eye infections. Dosage and frequency of administration too are an important factor to make a decision simplicity of treatment.
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